Description
Molecular Formula: C529H664F12N176Na43O316P43S6
Molecular Weight: 17,284.72 g/mol.
CAS: 1639324-58-5
Purity: Greatre than 98%
It has the following structural formula: is a small interfering RNA (siRNA) directed to PCSK9 (proprotein convertase subtilisin kexin type 9) mRNA.
Inclisiran contains a covalently linked ligand containing three Nacetylgalactosamine (GalNAc) residues. With one exception, the 2'ribose moieties of the inclisiran sodium are present as 2'-F or 2'-OMe ribonucleotide. In addition, six of the terminal phosphodiester backbones are present as phosphorothioate linkages