HCG - 5000 IU

STRUCTURE

HCG  α

ala-pro-asp-val-gln-asp-cys-pro-glu-cys-thr-leu-gIn-glu-asp-pro-phe-phe-ser-gln-pro-gly-ala-pro-ile-leu-gln-cys-met-gly-cys-cys-phe-ser-arg-ala-tyr-pro-thr-pro-leu-arg-ser-lys-lys-thr-met-leu-val-gln-lys-asn-val-thr-ser-glu-ser-thr-cys-cys-val-ala-lys-ser-tyr-asn-arg-val-thr-val-met-gly-gly-phe-lys-val-glu-asn-his-thr-ala-cys-his-cys-ser-thr-cys-tyr-tyr-his-lys-ser

HCG  β

ser-lys-glu-pro-leu-arg-pro-arg-cys-arg-pro-ile-asn-ala-thr-leu-ala-val-glu-lys-glu-gly-cys-pro-val-cys-ile-thr-val-asn-thr-thr-ile-cys-ala-gly-tyr-cys-pro-thr-met-thr-arg-val-leu-gln-gly-val-leu-pro-ala-leu-pro-gln-val-val-cys-asn-tyr-arg-asp-val-arg-phe-glu-ser-ile-arg-leu-pro-gly-cys-pro-arg-gly-val-asn-pro-val-val-ser-tyr-ala-val-ala-leu-ser-oys-gln-cys-ala-leu-cys-arg-arg-ser-thr-thr-asp-cys-gly-gly-pro-lys-asp-his-pro-leu-thr-cys-asp-asp-pro-arg-phe-gln-asp-ser-ser-ser-ser-lys-ala-pro-pro-pro-ser-leu-pro-ser-pro-ser-arg-leu-pro-gly-pro-ser-asp-thr-pro-ile-leu-pro-gln

Molecular Formula: C1105H1770N318O336S26

Molecular Weight: 25719.70 g/mol

CAS Number: 9002-61-3

Peptide purity: Greater than 98%

Other details: No TFA Salt

Storage: Lyophilized peptide must be stored at -20°C and peptide solution at +4°C

DESCRIPTION

HCG is a glycoprotein hormone naturally produced by the placenta during pregnancy, but it is also used therapeutically to stimulate testosterone production and support fertility in both men and women. In the male body, HCG mimics the action of luteinizing hormone (LH), stimulating the Leydig cells in the testes to produce testosterone and maintain spermatogenesis. In the female body, HCG is primarily used to induce ovulation and improve fertility.

Increase in Testosterone Production

HCG (human chorionic gonadotropin) acts similarly to luteinizing hormone (LH), which is crucial for stimulating testosterone production in the testes. In males, HCG binds to receptors on Leydig cells, located in the testes, activating testosterone production through the adenylate cyclase pathway. This signaling cascade leads to the conversion of cholesterol into testosterone, a critical process for reproductive function and maintaining testosterone levels in the blood. By increasing endogenous testosterone levels, HCG can correct dysfunctions associated with low hormone levels, such as hypogonadism. HCG therapy is particularly useful for men with low testosterone, who experience symptoms such as fatigue, reduced sexual desire, muscle mass loss, and depression. Additionally, since HCG stimulates endogenous testosterone production, it is often used as a treatment to maintain fertility in men taking exogenous testosterone, avoiding the complete suppression of the hypothalamic-pituitary-testicular axis.

Improvement of Male Fertility

HCG is widely used as a therapy to improve male fertility. In men, it stimulates the production of testosterone, which is essential for spermatogenesis. Spermatogenesis, the process of sperm production in the seminiferous tubules of the testes, depends on the presence of testosterone near Sertoli cells. Low testosterone levels can impair sperm production, reducing fertility. HCG, mimicking the action of luteinizing hormone (LH), can increase testosterone production locally in the testes, restoring normal spermatogenic function. This is particularly useful in men with oligospermia (low sperm count) or azoospermia (absence of sperm). Furthermore, HCG can be combined with other therapies such as human menopausal gonadotropin (HMG) to maximize the effect on fertility. Treatment with HCG therefore improves reproductive capacity, especially in patients with hypogonadotropic hypogonadism.

Increase in Testicular Volume

One of the side effects of prolonged use of exogenous testosterone is testicular atrophy, which occurs when the testes stop producing testosterone and sperm due to negative feedback on the hypothalamic-pituitary-testicular axis. HCG, acting as a stimulator of Leydig cells, can restore natural testosterone production in the testes and consequently their volume. Administration of HCG reactivates the physiological functions of the testes, leading to an increase in their volume and preventing or reversing testicular atrophy associated with the use of anabolic steroids or exogenous testosterone. This effect is important not only for maintaining fertility but also for preserving the long-term health of male reproductive organs. Studies have shown that treatment with HCG in patients with testicular atrophy significantly improves testicular morphology and function over time, restoring normal testicular volume.

Support in Post-Cycle Therapy (PCT)

In the context of bodybuilding or anabolic steroid use, HCG is often used as part of post-cycle therapy (PCT). During steroid cycles, the introduction of exogenous testosterone suppresses endogenous testosterone production, causing testicular atrophy and, in some cases, infertility. HCG is administered during the post-cycle phase to stimulate Leydig cells to resume endogenous testosterone production, thus preventing the negative effects of suppressing the hypothalamic-pituitary-testicular axis. In a well-structured PCT, HCG is usually combined with other drugs such as clomiphene or tamoxifen, which help restore normal function of the hormonal axis. The use of HCG during PCT accelerates the recovery process, preventing muscle mass loss and improving quality of life after anabolic steroid cycles. Its administration is particularly useful for preventing long-term side effects such as steroid-induced secondary hypogonadism.

Improvement of Erection Quality and Libido

Another indirect benefit of HCG in men is the improvement of erection quality and libido. Since HCG increases testosterone levels, it can enhance sexual desire and erectile function in men with hypogonadism or low testosterone levels. Testosterone plays a fundamental role in maintaining male sexual function, influencing libido and the ability to achieve and maintain an erection. HCG, by stimulating endogenous testosterone production, can therefore help improve these functions in patients with issues related to low hormone levels. Clinical studies have shown that treatment with HCG leads to an improvement in sexual desire and satisfaction in patients treated for hypogonadism. Furthermore, HCG has been successfully used to improve symptoms of erectile dysfunction associated with low testosterone levels, although it is not specifically a treatment for erectile dysfunction.

Support for Muscle Mass and Bone Density

The testosterone production induced by HCG not only affects reproductive health but is also essential for maintaining good muscle mass and bone density. Testosterone is an anabolic hormone that stimulates muscle tissue growth, improving protein synthesis and nitrogen retention, which are essential for the development and maintenance of muscle mass. HCG, by increasing testosterone levels, can help preserve or improve muscle mass, especially in men who have experienced a reduction in testosterone levels due to age or steroid use. In addition, testosterone plays a fundamental role in maintaining bone density, stimulating the activity of osteoblasts (the cells that form bones) and preventing bone degradation. In patients with low testosterone levels, HCG can therefore help prevent bone mass loss and reduce the risk of osteoporosis, a common condition in men with hypogonadism.

Regulation of Menstrual Cycle and Ovulation in Women

In women, HCG is mainly used to induce ovulation and regulate the menstrual cycle. The mechanism of action of HCG in women is similar to that of luteinizing hormone (LH), which stimulates ovulation during the menstrual cycle. HCG is administered in infertility treatments, particularly in assisted reproduction techniques, such as controlled ovarian stimulation. The peak of HCG mimics the natural LH surge, triggering the release of the mature egg from the ovary, thus facilitating conception. Additionally, HCG can support the corpus luteum in producing progesterone, essential for maintaining the endometrium and facilitating embryo implantation. In some women, HCG is also used to regulate irregular menstrual cycles and improve ovulation quality, thereby increasing the chances of success in fertility treatments.

Metabolic Support

HCG also has an indirect effect on metabolism due to increased testosterone. Testosterone is known to influence body composition, promoting an increase in muscle mass and a reduction in body fat. HCG, by stimulating endogenous testosterone production, can therefore have a positive impact on metabolism, improving the efficiency with which the body utilizes nutrients. This is particularly important for men with low testosterone levels, who often experience an increase in visceral fat and a reduction in lean mass. Some studies suggest that HCG can improve insulin sensitivity and glucose tolerance, thereby reducing the risk of metabolic syndrome and type 2 diabetes. However, the use of HCG as a weight loss treatment is controversial, and its direct effect on metabolism is mainly related to hormonal action rather than direct efficacy as a slimming agent.

Maintenance of Testicular Function During Exogenous Testosterone Therapy

When men take exogenous testosterone, their body stops natural testosterone production through negative feedback on the hypothalamic-pituitary-testicular axis. This leads to the suppression of Leydig cells in the testes, causing testicular atrophy and potentially affecting fertility. HCG can prevent or reduce these side effects by maintaining active testosterone production in the testes during exogenous testosterone therapy. This practice is commonly used in men who wish to maintain fertility during long-term treatment with testosterone or steroids. HCG allows for the preservation of sperm production and the avoidance of complete testicular atrophy. Maintaining testicular function through the use of HCG reduces long-term risks of infertility and other negative effects associated with suppression of the endocrine axis.

Anti-Aging Effect

HCG has a potential anti-aging impact due to its ability to increase testosterone levels. Testosterone plays a fundamental role in maintaining energy, vitality, bone density, muscle strength, and cognitive function, all of which tend to decline with age. Supplementation with HCG can help improve the quality of life in older people with low testosterone levels, promoting greater physical and mental energy. Although HCG is not commonly used as an anti-aging treatment per se, its stimulating effect on endogenous testosterone production can have side benefits that slow some aging processes, such as muscle mass loss, reduced bone density, and decreased sexual desire.

Effects on Mood and Vitality

HCG can significantly improve mood and vitality in men with low testosterone levels. Testosterone is closely linked to mood regulation, and its deficiency can lead to symptoms of depression, irritability, and chronic fatigue. By increasing testosterone production, HCG can help improve mood and overall well-being. Clinical studies have shown that men treated with HCG report improvements in energy levels, motivation, and mood tone. This positive effect is particularly relevant for men with hypogonadism, who often experience emotional changes due to testosterone deficiency.

DISCLAIMER

This product is intendend for lab research and development use only. These studies are performed outside of the body. This product is not medicines or drugs and has not been approved by the FDA or EMA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals.

All product information provided on this website is for informational and educational purposes only.