SERMORELIN - 2mg
Sermorelin is an analog of Growth Hormone-Releasing Hormone (GHRH) clinically used to evaluate and enhance the natural secretion of growth hormone (GH). Through its mechanism of action, Sermorelin provides numerous health benefits, including:
Increased bone density
Reduction of scarring after a heart attack
Alleviation of dementia-related symptoms
Improvement in chronic conditions
Enhanced kidney function
Reduction in seizure activity
Description
STRUCTURE
Sequence: Tyr-DL-Ala-DL-Asp-DL-Ala-DL-xiIle-DL-Phe-DL-xiThr-DL-Asn-DL-Ser-DL-Tyr-DL-Arg-DL-Lys-DL-Val-DL-Leu-Gly-DL-Gln-DL-Leu-DL-Ser-DL-Ala-DL-Arg-DL-Lys-DL-Leu-DL-Leu-DL-Gln-DL-Asp-DL-xiIle-DL-Met-DL-Ser-DL-Arg
Molecular Formula: C149H246N44O42S
Molecular Weight: 3357.933 g/mol
Peptide Purity: greater than 98%
Other details: No TFA Salt
DESCRIPTION
Sermorelin is a synthetic peptide derived from Growth Hormone-Releasing Hormone (GHRH). It works by stimulating the pituitary gland to naturally produce and release growth hormone. The effects of Sermorelin are similar to those of growth hormone (GH), including increased muscle mass, stimulation of long bone growth, and reduction of adipose tissue. However, the side effects of Sermorelin are significantly reduced compared to exogenous GH administration.
One of the key advantages of Sermorelin is that its use is governed by the body's natural feedback mechanisms. This means that Sermorelin stimulates GH release only when needed, avoiding the risks associated with excess GH administration. Furthermore, research shows that Sermorelin does not cause tachyphylaxis, a phenomenon where the body becomes accustomed to a drug and requires progressively higher doses to achieve the same effects. On the contrary, the use of Sermorelin can actually increase the production of GHRH receptors, ensuring consistent effectiveness over time.
Increased bone density
Research has shown that Sermorelin supports bone health by stimulating the release of growth hormone, which in turn promotes the production of IGF-1. This growth factor is crucial for bone metabolism, as it enhances bone formation and mineralization. Over time, this can lead to significant improvements in bone density, making bones less fragile and more resistant to fractures, particularly with age.
Reduction of scarring after a heart attack
Sermorelin has been associated with improved tissue regeneration in cardiac tissues. The growth hormone and IGF-1 released due to Sermorelin stimulation play a significant role in repairing damaged tissues. Specifically, they help reduce scar formation in heart tissue after a heart attack, facilitating a more effective recovery and improving overall heart function.
Alleviation of dementia-related symptoms
IGF-1, produced in response to Sermorelin administration, has shown neuroprotective properties. This growth factor appears to enhance neuronal plasticity and reduce brain inflammation. These effects can lead to improved cognitive functions such as memory and focus, offering potential benefits in addressing symptoms associated with neurodegenerative conditions like dementia.
Improvement in chronic conditions
One of Sermorelin’s most promising effects is its ability to support cellular regeneration and modulate chronic inflammation. These processes are fundamental in managing long-term conditions, such as metabolic syndromes. By stimulating the natural production of GH and IGF-1, Sermorelin helps restore cellular balance and improve overall well-being.
Enhanced kidney function
Studies suggest that Sermorelin may positively affect kidney health. By promoting the regeneration of nephrons, the functional units of the kidney, and improving renal blood flow, Sermorelin supports the maintenance of proper kidney function. This can be particularly beneficial in conditions involving mild kidney stress or dysfunction.
Reduction in seizure activity
Sermorelin, through the effects of growth hormone and IGF-1, can have a beneficial impact on the central nervous system. These growth factors improve neuronal function, reduce abnormal excitability in the nervous system, and promote electrical stability in the brain. Such effects may help reduce the frequency and severity of seizures, making it a valuable focus for neurological research.
REFERENCES
A. Prakash et al., "Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency" [PubMed]
R.F. Walker "Sermorelin: A better approach to management of adult-onset growth hormone insufficiency?" [PubMed]
D.K. Sinha et al., "Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males" [National Library of Medicine]
J. Jimenez et al., "A new approach to the treatment of acute myeloid leukaemia targeting the receptor for growth hormone-releasing hormone" [PubMed]
P. Wilton et al., "Pharmacokinetics of growth hormone-releasing hormone(1-29)-NH2 and stimulation of growth hormone secretion in healthy subjects after intravenous or intranasal administration" [PubMed]
DISCLAIMER
This product is intendend for lab research and development use only. These studies are performed outside of the body. This product is not medicines or drugs and has not been approved by the FDA or EMA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals.
All product information provided on this website is for informational and educational purposes only.