Vanadium is used for treating diabetes, high cholesterol, heart disease, tuberculosis, syphilis, a form of “tired blood” (anemia), water retention (edema); for improving athletic performance in weight training.
Hyperglycemia can lead to diabetic problems and their socio-economic burden. Various tissues which have been exposed to high concentration of glucose may lead to changes in cell signaling, increment of oxidizing species or significant reduction in antioxidant capacity. Also, hyperglycemia has critical role in Advanced Glycation End products (AGEs) formation, as well as, secretion of the pro-inflammatory cytokines and cellular death.
Diabetic Kidney Disease (DKD) is one of the most common complications of diabetes, and its severity has increased throughout the world over the last decade due to the growing trend of diabetes, as it is becoming a major cause of death and mortality.
Vanadyl sulfate has been used in humans in the form of insulin-mimetic salt and thus controls both Diabetes type 1 and type 2. Vanadyl sulfate protects from beta cells of Langerhans, and therefore provides insulin production and secretion that can improve blood glucose levels.