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hsBCL9CT-24 is a synthetic research peptide associated with the investigation of Wnt/β-catenin signaling and the β-catenin/BCL9 interaction. β-Catenin is the central transcriptional effector of the canonical Wnt pathway, which regulates cellular proliferation, differentiation, and tissue homeostasis. Persistent activation of this pathway can support abnormal growth and tumor-associated transcriptional programs. Within the nucleus, β-catenin cooperates with transcription factors and coactivators, including BCL9, to regulate Wnt-responsive genes. Interfering with the β-catenin/BCL9 interface is therefore an experimental approach for investigating the molecular mechanisms that sustain oncogenic Wnt signaling. Research involving hsBCL9CT-24 has contributed to the study of peptide-based inhibitors targeting this interaction. This field explores how disruption of β-catenin-associated transcriptional complexes may influence tumor cell behavior and the surrounding immune microenvironment.