L-GLUTATHIONE - 10ml/500mg - Spray

ADVANCED DELIVERY SYSTEM - CELL PENETRATING PEPTIDE TECHNOLOGY 

This product utilizes advanced delivery technology incorporating calibrated cell-penetrating peptide (CPP) systems. The formulation is engineered to support efficient and targeted intracellular delivery of active ingredients, contributing to enhanced transport performance and bioavailability.

SPECIFICATIONS

Product Code: LGL500S

Sequence: γ-Glu-Cys-Gly

Molecular Formula: C10H17N3O6S

Molecular Weight: 307.33 g/mol

CAS No: 170-18-8

Purity: Technical / Research Grade ≥98%

Other details: No TFA Salt

Form: Liquid Solution

Color: Clear / Slightly opalescent

Total Content: 10 mL / 500 mg

Concentration: 50 mg/mL

Approximate Sprays per Bottle: ~82

Approximate Peptide per Spray: ~6 mg

Vehicle / Carrier System: Proprietary carrier system

Storage Temperature: 4°C (Do not freeze)

Source: Synthetic

Safety classification: Standard handling.

DESCRIPTION

L-Glutathione is a naturally occurring tripeptide composed of three amino acids: glutamate, cysteine, and glycine. It is ubiquitously present in human cells and has been extensively studied in biochemical and cellular research due to its central role in maintaining intracellular redox balance and overall cellular homeostasis. Glutathione is synthesized endogenously and is considered one of the most important non-enzymatic antioxidants within the cell. Its primary function in experimental systems involves the neutralization of reactive oxygen species (ROS) and the protection of cellular structures from oxidative stress–related damage.

In research and preclinical models, L-Glutathione has been shown to participate in a wide range of physiological and biochemical processes. These include detoxification pathways, regulation of immune signaling, maintenance of mitochondrial integrity, and modulation of inflammatory responses. Glutathione acts as a critical cofactor for several enzymatic systems, including glutathione peroxidases and glutathione S-transferases, which are involved in the reduction of peroxides and the conjugation of xenobiotics for cellular clearance. Because of this, glutathione has been widely investigated in studies focusing on liver metabolism, environmental toxin exposure, and cellular defense mechanisms.

L-Glutathione has also been studied for its role in maintaining protein structure and function. By preserving thiol groups in their reduced state, glutathione contributes to correct protein folding and helps prevent protein oxidation and aggregation. In addition, experimental data suggest that glutathione levels influence cellular signaling pathways related to apoptosis, cell proliferation, and stress adaptation. Declines in intracellular glutathione concentrations have been associated in research models with increased oxidative burden and altered cellular resilience.

Due to its fundamental involvement in cellular protection and metabolic regulation, L-Glutathione has been investigated across multiple research domains, including aging biology, immunology, neurology, and mitochondrial research. Various experimental delivery methods and formulations have been explored in order to better understand glutathione stability, transport, and bioavailability within different biological systems. These investigations have contributed to its continued relevance as a reference molecule in oxidative stress and cellular defense research.

REFERENCES

G. Wu et al., " Glutathione metabolism and its implications for health" [PubMed]

S. Sonthalia et al., "Glutathione as a skin whitening agent: Facts, myths, evidence and controversies" [PubMed]

K.C. Yang et al., "l-Glutathione enhances antioxidant capacity of hyaluronic acid and modulates expression of pro-inflammatory cytokines in human fibroblast-like synoviocytes" [PubMed]

A.P. de Oliveira et al., "L-glutathione 1% promotes neuroprotection of nitrergic neurons and reduces the oxidative stress in the jejunum of rats with Walker-256-bearing tumor" [PubMed]

D.A. Averill-Bates "The antioxidant glutathione" [PubMed]

G. Santacroce et al., "Glutathione: Pharmacological aspects and implications for clinical use in non-alcoholic fatty liver disease" [PMC]

T.F. Alzahrani et al., "Exploring the Safety and Efficacy of Glutathione Supplementation for Skin Lightening: A Narrative Review" [PMC]

B.D. Hristov "The Role of Glutathione Metabolism in Chronic Illness Development and Its Potential Use as a Novel Therapeutic Target" [PMC]

L. Kennedy et al., "Role of Glutathione in Cancer: From Mechanisms to Therapies" [PubMed]

S. Weschawalit et al., "Glutathione and its antiaging and antimelanogenic effects" [PubMed]

H.Y. Forman et al., "Glutathione: Overview of its protective roles, measurement, and biosynthesis" [PMC]

DISCLAIMER

This product is intendend for lab research and development use only. These studies are performed outside of the body. This product is not medicines or drugs and has not been approved by the FDA or EMA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals.

All product information provided on this website is for informational and educational purposes only.