HGH (191 AA), RECOMBINANT - 10 IU

SPECIFICATIONS

Product Code: HGR010

191 amino acids and two disulfide bonds (C53-C165; C182-C189)

Molecular Formula: C990H1528N262O300S7

Molecular Weight: 22125 g/mol

CAS No.: 12629-01-5

Purity: Technical / Research Grade 99%

Other details: No TFA Salt

Form: Lyophilized powder

Color: White

Storage temperature: -20°C

Source: Synthetic

Safety classification: Standard handling

DESCRIPTION

Recombinant Human Growth Hormone (HGH) is a protein hormone composed of 191 amino acids, structurally identical to endogenous human growth hormone. It is produced using recombinant DNA technology and is widely utilized in controlled research environments. Structurally, HGH is a single-chain polypeptide characterized by four alpha-helical domains, which are essential for receptor interaction and activation of downstream signaling pathways. Its molecular weight is approximately 22 kDa.

HGH is studied for its interaction with growth hormone receptors (GHR), which are expressed across multiple tissues. Upon receptor binding, it activates intracellular signaling cascades, including the JAK/STAT and MAPK/ERK pathways, which regulate cellular communication, gene expression, and metabolic coordination. Its activity is associated with system-wide regulatory processes involving endocrine signaling, cellular turnover, and integrative physiological responses. Many of its downstream effects are mediated through insulin-like growth factor pathways, which play a role in broader signaling networks related to metabolic and tissue-level regulation.

Due to its well-characterized structure and extensive involvement in multi-system signaling, HGH remains a central molecule of interest in research models focused on endocrine function, metabolic regulation, and cross-tissue communication processes.

REFERENCES

All observations described above originate from in vitro systems, animal studies, or other preclinical experimental models. They are intended solely to support basic research into molecular, cellular, and physiological mechanisms and do not imply therapeutic, diagnostic, or preventive applications in humans or animals.

L.M. Fryklund et al., "Recombinant human growth hormone" [Pubmed]

A. Metha et al., "The use of somatropin (recombinant growth hormone) in children of short stature" [PubMed]

F. Salomon et al., "The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency" [PubMed]

P. Gou et al., "A Real-World Study of Recombinant Human Growth Hormone in the Treatment of Idiopathic Short Stature and Growth Hormone Deficiency" [PubMed]

F.G Tresguerres et al., "Growth Hormone As Antiaging Factor in Old Bones" [PubMed]

U. Meinhardt et al., "The effects of growth hormone on body composition and physical performance in recreational athletes: a randomized trial" [PubMed]

K. Hermansen et al., "Impact of GH administration on athletic performance in healthy young adults: A systematic review and meta-analysis of placebo-controlled trials" [PubMed]

DISCLAIMER

This product is intendend for lab research and development use only. These studies are performed outside of the body. This product is not medicines or drugs and has not been approved by the FDA or EMA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals.

All product information provided on this website is for informational and educational purposes only.

INDEPENDENT THIRD-PARTY CERTIFICATE OF ANALYSIS SHOWN FORREFERENCE PURPOSES. ANALYTICAL RESULTS MAY VARY SLIGHTLY BETWEEN BATCHES.