BPC-157 ARG - 10ml/30mg - Spray

ADVANCED DELIVERY SYSTEM - CELL PENETRATING PEPTIDE TECHNOLOGY 

This product utilizes advanced delivery technology incorporating calibrated cell-penetrating peptide (CPP) systems. The formulation is engineered to support efficient and targeted intracellular delivery of active ingredients, contributing to enhanced transport performance and bioavailability.

SPECIFICATIONS 

Product Code: B73010S

Sequence: Gly-Glu-Pro-Pro-Pro-Gly- Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val x 2 x L-Arg

Molecular Formula: C62H98N16O22

Molecular Weight (peptide): 1418.70 g/mol

CAS: 137525-51-0

Purity: Technical / Research Grade ≥98%

Other details: No TFA Salt

Form: Liquid Solution

Color: Clear / Slightly opalescent

Total Content: 10 mL / 30 mg

Concentration: 3 mg/mL

Approximate Sprays per Bottle: ~82

Approximate Peptide per Spray: ~365 mcg

Vehicle / Carrier System: Proprietary carrier system

Storage Temperature: 4°C (Do not freeze)

Source: Synthetic

Safety classification: Standard handling

DESCRIPTION

BPC-157 is a synthetic peptide derived from a sequence naturally present in gastric juice, where endogenous BPC peptides are involved in maintaining gastrointestinal mucosal integrity. In preclinical research models, BPC-157 has been used to investigate mechanisms related to epithelial barrier stability, extracellular matrix organization, and tissue repair signaling under experimental conditions.

Fibroblast activity and extracellular matrix research (preclinical)

In cell culture systems and animal models, BPC-157 has been studied for its influence on fibroblast proliferation and migration, two key cellular processes involved in wound healing and connective tissue remodeling. Fibroblasts are responsible for the deposition of extracellular matrix components such as collagen, fibrin, and elastin, and experimental modulation of their activity is commonly used to study tissue regeneration mechanisms.

Angiogenesis and ischemia-related models (preclinical)

BPC-157 has been investigated in preclinical angiogenesis assays to explore its effects on endothelial cell behavior and collateral vessel formation. In animal models of ischemic injury, experimental exposure to BPC-157 has been associated with altered vascular responses, which are used to study blood supply restoration and tissue recovery dynamics in gastrointestinal, cardiovascular, neural, and musculoskeletal research contexts.

Musculoskeletal and connective tissue research (preclinical)

In in vitro and in vivo models of tendon, ligament, and bone injury, BPC-157 has been examined for its role in cell recruitment, vascular density, and connective tissue organization. These experimental systems are used to explore why tissues with limited blood supply exhibit delayed repair and how angiogenesis and fibroblast migration contribute to structural recovery under laboratory conditions.

Oxidative stress and inflammatory signaling models (preclinical)

In rodent models, BPC-157 has been studied for its interaction with oxidative stress markers, including pathways involving nitric oxide signaling and lipid peroxidation indices. These studies investigate antioxidant-related mechanisms and their contribution to tissue protection in experimental gastrointestinal and systemic inflammation models.

Drug interaction and tissue stress research (preclinical)

BPC-157 has also been explored in preclinical models assessing tissue responses to pharmacologically induced stress, including systems designed to study adverse tissue effects associated with various compound classes. These investigations focus on cellular resilience, barrier protection, and repair signaling, rather than mitigation of drug effects in clinical settings.

Neurobiology and brain–gut axis research (preclinical)

Experimental studies have examined BPC-157 in preclinical neurobiological models to explore interactions between peripheral tissues and central signaling pathways, including serotonergic and dopaminergic systems. These models are used to study brain–gut communication and stress-related signaling, without implying behavioral or therapeutic outcomes.

REFERENCES

All information presented above is derived from in vitro experiments, animal studies, and other preclinical research models. These data are intended solely for basic scientific investigation of biological mechanisms and do not imply any therapeutic, diagnostic, preventive, or clinical use in humans or animals. 

M. Hsieh et al., "Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation" [Journal of Molecular Medicine]

J. Vukojevic et al.,  "Rat inferior caval vein (ICV) ligature and particular new insights with the stable gastric pentadecapeptide BPC 157" [Vascular Pharmacology]

N. Jelovac et al., "Pentadecapeptide BPC 157 attenuates disturbances induced by neuroleptics: the effect on catalepsy and gastric ulcers in mice and rats" [PubMed]

D. Strinic et al., "BPC 157 counteracts QTc prolongation induced by haloperidol, fluphenazine, clozapine, olanzapine, quetiapine, sulpiride, and metoclopramide in rats" [PubMed]

K. Skrlec et al., "Engineering recombinant Lactococcus lactis as a delivery vehicle for BPC-157 peptide with antioxidant activities" [PubMed]

C. Chang et al., "The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration" [PubMed]

S. Seiwerth et al., "BPC 157 and Standard Angiogenic Growth Factors. Gastrointestinal Tract Healing, Lessons from Tendon, Ligament, Muscle and Bone Healing" [PubMed]

P. Sikiric et al., "Novel Cytoprotective Mediator, Stable Gastric Pentadecapeptide BPC 157. Vascular Recruitment and Gastrointestinal Tract Healing" [PubMed]

DISCLAIMER

This product is intendend for lab research and development use only. These studies are performed outside of the body. This product is not medicines or drugs and has not been approved by the FDA or EMA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals.

All product information provided on this website is for informational and educational purposes only.